This product is for in vitro (diagnostic) use only. Not for human or animal consumption.
Fibrinogen, also known as Factor I, is a key plasma protein critical for blood coagulation, where it is transformed into fibrin by the enzyme thrombin. With a molecular weight of around 340 kDa, fibrinogen is composed of three distinct pairs of polypeptide chains linked by disulfide bonds. The α-chain has a molecular weight of approximately 63.4 kDa, the β-chain around 56 kDa, and the γ-chain about 47 kDa. These chains are interconnected at the N-termini by dimeric disulfide knot (DSK), with an additional DSK present elsewhere in the structure. Fibrinogen contains roughly 4% carbohydrates.
Fibrinogen from any mammalian species typically interacts with thrombin from any other mammalian source, resulting in clot formation when thrombin from one species is introduced into another.
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